Angry?

Psalm 80:4, the second half, has had me thinking all day.  I have a question for you.  What would make God angry at the prayer of His people?  I started to answer that by thinking through all that Israel had done to raise God’s ire.  Then I begin to wonder if the Church, God’s people, is doing the same thing now.

But the problem is, we are different than Israel.  We are covered by the blood of His Son.  Can we make God angry with our prayer now?  If we can what are the implications of that?

What do you think?  How do you support your thought from Scripture?